Genes for common diseases

Genes and Diseases

The science of medical genetics is progressing rapidly. The practical importance of this pro­gress should be considered by medical doctors. Both genetic and environmental factors are involved in the abnormail phenotypes considered diseases. The relative significance of the two factors varies from disease to disease. All di­seases can be viewed as falling on a spectrum in this regard. Hereditary...

OCTN genes: Susceptibility genes for autoimmune diseases?

El estudio genético de las enfermedades autoinmunes de base poligénica (artritis reumatoide, enfermedad inflamatoria intestinal, etc) ha evolucionado desde la identificación, mediante estudios de ligamiento, de regiones del genoma implicadas en la susceptibilidad, a la identificación dentro de esas zonas, mediante estudios de asociación, de las variantes concretas en genes específicos que están...

Emergency Management of Common Diseases in Children

Acute respiratory infections, diarrhea and fever are very common in children below the age of five years. All children suffer from these illnesses several times each year. However, during natural disasters like floods children are even more vulnerable to these diseases and death. Pneumonia, diarrhea, measles and malaria, and associated malnutrition, are responsible for over 60% deaths in childr...

Simple Sequence Repeat Dna Markers Linked with Genes for Resistance to Major Diseases of Common Bean

Heterogeneity of linkage disequilibrium in human genes has implications for association studies of common diseases.

Linkage disequilibrium (LD) is the central concept of genetic association studies. Although LD has been shown not to be uniformly distributed across the genome, limited information is available about the characteristics of LD within candidate genes at large. We screened coding and regulatory regions of 50 candidate genes for cardiovascular diseases and identified 228 polymorphisms. The overall ...